Allergy shots are a long-term immunotherapy treatment that exposes your immune system to small, controlled amounts of specific allergens. Unlike medications that address symptoms as they occur, allergy shots gradually change how your body responds to allergens. An allergist may discuss this option with you if your allergic reactions persist despite avoidance strategies or medications, or if allergy medications cause unwanted side effects. Because the treatment follows a structured schedule, follow-up visits play a central role in the process. Here’s information on immunotherapy shots and what to expect from follow-up care:
Reducing Airborne Allergen Reactions
Allergic reactions occur when your immune system identifies a harmless substance as a threat. In response, your body releases histamine and other chemicals that can cause sneezing, congestion, itchy eyes, and other symptoms. Allergy shots introduce tiny amounts of the allergens that trigger your reactions. Repeated exposure may help your immune system become less sensitive to these substances over time. The goal of allergy shot treatments is to gradually desensitize the body, and each shot supports this process.
Allergy shots are commonly used to address airborne allergens, including:
- Tree, Grass, and Weed Pollen
- Dust Mites
- Mold Spores
- Pet Dander
- Cockroach Particles
Some allergists also use immunotherapy for insect sting allergies, but they do not treat food allergies. Your allergist can review your history and symptoms to determine whether your allergens are appropriate for this type of treatment.
Customizing Shot Formulas
Because allergy shots are not a one-size-fits-all treatment, your allergist will perform allergy testing before starting treatment to identify the substances that trigger your reactions. Skin prick tests and blood tests are two common methods. Test results show which allergens affect you and how strongly your immune system reacts to each one. Your allergist uses these results to create a serum, or extract, tailored to your sensitivities. A person with grass and dust mite allergies will receive a different formula than a person allergic to mold and cat dander; no two treatment plans are exactly alike.
An expert calculates your dose and mixes your serum in an on-site lab. This process follows strict quality-control standards that exceed the minimum requirements mandated by the American Academy of Allergy, Asthma & Immunology (AAAAI). Preparing the serum on-site lets your care team adjust your formula as your treatment progresses, supporting consistency and accuracy in each vial.
Getting Follow-up Care
To build immunity, you will need shots on a consistent schedule that gradually desensitizes your immune system. This means allergy shots require regular visits to your allergist’s office, and treatment typically occurs in two phases. During the build-up phase, you will usually receive one to two shots each week. Your provider gradually increases the dose in each shot. This phase often lasts several months, depending on how your body responds to the increasing doses.
Once you reach your target dose, you will enter the maintenance phase. During this phase, you usually get shots less often, such as every two to four weeks. Immunotherapy builds up over time, so it can take three to five years or longer to reduce or stop your symptoms.
Follow-up visits also serve other purposes beyond receiving shots. Your provider can monitor your response, check for reactions, and adjust your dose when needed. Most offices ask you to wait about 30 minutes after each injection while staff observes you for signs of a reaction. Missing appointments may require your provider to lower your dose before continuing, so attending your consistent schedule helps keep treatments on track.
Learn More About Allergy Shots
Allergy shots are a long-term commitment that requires regular follow-up visits. Each appointment allows your care team to deliver your customized serum, adjust your dosage, and monitor your progress. If airborne allergens affect your daily life, an allergist can evaluate your symptoms and determine whether immunotherapy is appropriate. To learn more about testing, treatment schedules, and what to expect from allergy shots, schedule a consultation with an allergy specialist.


